If, like me, you have this annoying problem where iTunes insists on launching every time you press a multimedia key on your keyboard (for instance play/pause/next/previous song) the fastest and most effective way to work around it is to get rid of iTunes completely:
- Move iTunes to the trash (from the applications folder);
- Move FrontRow to the trash (from the applications folder);
- Empty the trash;
- If emptying the trash fails due to the iTunesHelper application being running do the following:
- Open terminal/console:
- Type “ps aux | grep iTunes”
- You should see the process in the list. Get it’s process id (PID)
- Type “kill -9 <pid>” to kill the process
- Empty the trash
- Extra step, remove iTunesHelper from the list of login items (system preferences -> accounts -> login items).
Use SongBird instead 
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